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Article

Pin1 and JNK1 cooperatively modulate TAp63γ.

FEBS open bio - 1 Mar 2021

Fan Xueying, He Wei, Hu Ke, Chen Huimin, Chen Li, Fan Shijie, Li Chenghua

Abstract excerpt

The p63 gene encodes at least 10 isoforms, which can be classified into TA and ∆N isotypes (TAp63 and ∆Np63 proteins) according to their differences at the N termini. TAp63γ is an important transcription factor. We previously reported that peptidyl-prolyl isomerase (PPI) Pin1 directly binds to TAp63γ protein and identified that serine 12 (S12 ) in the transactivation domain (TAD) of TAp63γ is required for...

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Identifiers

PMID: 33548094
DOI: 10.1002/2211-5463.13109
PMCID: PMC7931219

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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