Article
DNA methylation profiling reveals the presence of population-specific signatures correlating with phenotypic characteristics.
Molecular genetics and genomics : MGG - 1 Jun 2017
Giri Anil K, Bharadwaj Soham, Banerjee Priyanka, Chakraborty Shraddha, Parekatt Vaisak, Rajashekar Donaka, Tomar Abhishek, Ravindran Aarthi, Basu Analabha, Tandon Nikhil, Bharadwaj Dwaipayan
Abstract excerpt
Phenotypic characteristics are known to vary substantially among different ethnicities around the globe. These variations are mediated by number of stochastic events and cannot be attributed to genetic architecture alone. DNA methylation is a well-established mechanism that sculpts our epigenome influencing phenotypic variation including disease manifestation. Since DNA methylation is an important determinant for...
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