Article
Coupled mixed model for joint genetic analysis of complex disorders with two independently collected data sets.
BMC bioinformatics - 5 Feb 2021
Wang Haohan, Pei Fen, Vanyukov Michael M, Bahar Ivet, Wu Wei, Xing Eric P
Abstract excerpt
BACKGROUND: In the last decade, Genome-wide Association studies (GWASs) have contributed to decoding the human genome by uncovering many genetic variations associated with various diseases. Many follow-up investigations involve joint analysis of multiple independently generated GWAS data sets. While most of the computational approaches developed for joint analysis are based on summary statistics, the joint...
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