Article
Molecular driver alterations and their clinical relevance in cancer of unknown primary site.
Oncotarget - 12 Jul 2016
Löffler Harald, Pfarr Nicole, Kriegsmann Mark, Endris Volker, Hielscher Thomas, Lohneis Philipp, Folprecht Gunnar, Stenzinger Albrecht, Dietel Manfred, Weichert Wilko, Krämer Alwin
Abstract excerpt
Cancer of unknown primary (CUP) is defined as metastatic solid malignancy where no primary tumor is detected despite appropriate staging. About 90% of CUP represent adenocarcinoma or undifferentiated carcinoma. Since therapy regimens are only modestly effective, identification of the molecular landscape of these neoplasms might be a promising approach to direct CUP therapy and aid in tumor classification. We...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.