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Mechanisms of Coronavirus Nsp1-Mediated Control of Host and Viral Gene Expression

2 Feb 2021

Abstract excerpt

Many viruses disrupt host gene expression by degrading host mRNAs and/or manipulating translation activities to create a cellular environment favorable for viral replication. Often, virus-induced suppression of host gene expression, including those involved in antiviral responses, contributes to viral pathogenicity. Accordingly, clarifying the mechanisms of virus-induced disruption of host gene expression is...

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PMID: 33540583
DOI: 10.3390/cells10020300

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