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IGF2BP2 Overexpression Indicates Poor Survival in Patients with Acute Myelocytic Leukemia

1 Jan 2018

Abstract excerpt

BACKGROUND/AIMS: IGF2BP2 has been reported to serve as an oncogene in various solid cancers. However, the role of IGF2BP2 in acute myelocytic leukemia (AML) is still unknown. METHODS: Public databases Gene Omnibus was used to evaluate the expression of IGF2BP2 in AML patients and healthy controls. In addition, primary cells from these two populations were prepared by Ficoll density centrifugation. Rt-qPCR and...

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PMID: 30513526
DOI: 10.1159/000495719

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