Article
Effect of metabolic genetic variants on long-term disease comorbidity in patients with type 2 diabetes.
Scientific reports - 2 Feb 2021
Abedian Shifteh, Abbasi Ali, de Boer Anthonius, Stricker Bruno H, Bakker Stephan J L, van der Harst Pim, Sedaghat Sanaz, Darvishian Maryam, Ikram M Arfan, Navis Gerjan, Dehghan Abbas, Pen Ido, Stolk Ronald P, Snieder Harold, Klungel Olaf H, Souverein Patrick, Alizadeh Behrooz Z
Abstract excerpt
Underlying genetic determinants contribute to developing type 2 diabetes (T2D) future diseases. The present study aimed to identify which genetic variants are associated with the incident of the major T2D co-morbid disease. First, we conducted a discovery study by investigating the genetic associations of comorbid diseases within the framework of the Utrecht Cardiovascular Pharmacogenetic studies by turning...
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