Article
Gene polymorphisms of Interleukin-4 in allergic rhinitis and its association with clinical phenotypes.
American journal of otolaryngology - 1 Jan 2000
Movahedi Masoud, Amirzargar Ali Akbar, Nasiri Rasoul, Hirbod-Mobarakeh Armin, Farhadi Elham, Tavakol Marzieh, Behniafard Nasrin, Ansaripour Bita, Moradi Batoul, Zare Ahad, Rezaei Nima
Abstract excerpt
BACKGROUND: Allergic rhinitis (AR) is an inflammatory disorder of the upper airway. T-helper (Th)2 cytokines seems to have major roles behind the scene of unpleasant symptoms resulted from AR. Expression of interleukin (IL)-4 and its receptor could be affected by single nucleotide polymorphisms (...
Topics
- Case-Control Studies
- Eosinophils
- Female
- Gene Frequency
- Genotype
- Haplotypes
- Homozygote
- Humans
- Interleukin-4
- Male
- Phenotype
- Polymerase Chain Reaction
- Polymorphism, Single Nucleotide
- Receptors, Interleukin-4
- Rhinitis, Allergic, Perennial