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Article

Genetic characterisation of adult primary pleomorphic uterine rhabdomyosarcoma and comparison with uterine carcinosarcoma.

Histopathology - 1 Aug 2021

Ashley Charles W, Da Cruz Paula Arnaud, Ferrando Lorenzo, Gularte-Mérida Rodrigo, Sebastiao Ana P M, Brown David N, Gazzo Andrea M, Pareja Fresia, Stylianou Anthe, Abu-Rustum Nadeem R, Reis-Filho Jorge S, Buehler Darya, Weisman Paul, Chiang Sarah, Weigelt Britta

Abstract excerpt

AIMS: To characterise the genetic alterations in adult primary uterine rhabdomyosarcomas (uRMSs) and to investigate whether these tumours are genetically distinct from uterine carcinosarcomas (UCSs). METHODS AND RESULTS: Three tumours originally diagnosed as primary adult pleomorphic uRMS were subjected to massively parallel sequencing targeting 468 cancer-related genes and RNA-sequencing. Mutational profiles...

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Source

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Identifiers

PMID: 33527450
DOI: 10.1111/his.14346
PMCID: PMC8286280

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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