Article
Interleukin 6(-174G/C) variant and its circulating levels in coronary artery disease patients and their first degree relatives.
Inflammation - 1 Apr 2014
Galimudi Rajesh Kumar, Spurthi Mrudula K, Padala Chiranjeevi, Kumar Kishore G, Mudigonda Saraswati, Reddy Srilatha G, Aiyengar Mohini T, Sahu Sanjib K, Rani Surekha H
Abstract excerpt
Interleukin-6 (IL-6) a pleiotropic cytokine is a central mediator of inflammation in the pathogenesis of coronary artery disease (CAD). Our aim is to evaluate the serum levels of IL-6 and C-reactive protein (CRP) and to analyze the IL-6 polymorphism in CAD patients and to identify the first-degree relatives (FDRs) at risk of the disease in comparison with healthy controls. Estimation of IL-6 levels by...
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