Article

GARD is a pan-cancer predictor of radiation therapy benefit

2020-12-22

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Despite advances in cancer genomics, radiation therapy (RT) is still prescribed based on an empiric one-size-fits-all paradigm. Previously, we proposed a novel algorithm using the genomic adjusted radiation dose (GARD) to personalize RT prescription dose based on the biological effect of a given physical RT dose, calculated using individual tumor genomics. We hypothesize that...

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Literature Corpus work: af696f68-b7be-5e74-a923-612826a672d7
DOI: 10.1101/2020.12.19.20248484

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