Article
Higher genome variability within metabolism genes associates with recurrent Clostridium difficile infection.
BMC microbiology - 28 Jan 2021
Kulecka Maria, Waker Edyta, Ambrozkiewicz Filip, Paziewska Agnieszka, Skubisz Karolina, Cybula Patrycja, Targoński Łukasz, Mikula Michał, Walewski Jan, Ostrowski Jerzy
Abstract excerpt
BACKGROUND: Clostridium difficile (C. difficile) is a major source of healthcare-associated infection with a high risk of recurrence, attributable to many factors such as usage of antibiotics, older age and immunocompromised status of the patients. C. difficile has also a highly diverse genome, which may contribute to its high virulence. Herein we examined whether the genome conservation, measured as...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.