Comparative genome and phenotypic analysis of three Clostridioides difficile strains isolated from a single patient provide insight into multiple infection of C. difficile.

doi:10.1186/s12864-017-4368-0

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Article

Comparative genome and phenotypic analysis of three Clostridioides difficile strains isolated from a single patient provide insight into multiple infection of C. difficile.

BMC genomics - 2 Jan 2018

Groß Uwe, Brzuszkiewicz Elzbieta, Gunka Katrin, Starke Jessica, Riedel Thomas, Bunk Boyke, Spröer Cathrin, Wetzel Daniela, Poehlein Anja, Chibani Cynthia, Bohne Wolfgang, Overmann Jörg, Zimmermann Ortrud, Daniel Rolf, Liesegang Heiko

Abstract excerpt

BACKGROUND: Clostridioides difficile infections (CDI) have emerged over the past decade causing symptoms that range from mild, antibiotic-associated diarrhea (AAD) to life-threatening toxic megacolon. In this study, we describe a multiple and isochronal (mixed) CDI caused by the isolates DSM 27638, DSM 27639 and DSM 27640 that already initially showed different morphotypes on solid media. RESULTS: The three...

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PMID: 29291715
DOI: 10.1186/s12864-017-4368-0
PMCID: PMC5749029

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