Article
The conserved alternative splicing factor caper regulates neuromuscular phenotypes during development and aging.
Developmental biology - 1 May 2021
Titus M Brandon, Wright Ethan G, Bono Jeremy M, Poliakon Andrea K, Goldstein Brandon R, Super Meg K, Young Lauren A, Manaj Melpomeni, Litchford Morgan, Reist Noreen E, Killian Darrell J, Olesnicky Eugenia C
Abstract excerpt
RNA-binding proteins play an important role in the regulation of post-transcriptional gene expression throughout the nervous system. This is underscored by the prevalence of mutations in genes encoding RNA splicing factors and other RNA-binding proteins in a number of neurodegenerative and neurodevelopmental disorders. The highly conserved alternative splicing factor Caper is widely expressed throughout the...
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