Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comprehensive somatosensory and neurological phenotyping of NCS1 knockout mice.

Scientific reports - 27 Jan 2021

Nguyen Lien D, Nolte Luca G, Tan Winston J T, Giuvelis Denise, Santos-Sacchi Joseph, Bilsky Edward, Ehrlich Barbara E

Abstract excerpt

Neuronal calcium sensor 1 (NCS1) regulates a wide range of cellular functions throughout the mammalian nervous systems. Altered NCS1 expression is associated with neurodevelopmental and neurodegenerative diseases. Previous studies focused on affective and cognitive behaviors in NCS1 knockout (KO) mice, but little is known about the physiological and pathological states associated with the loss of NCS1 in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Behavior, Animal
Share to Mice, Knockout

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Motor Activity

Share to Neuropeptides

Share to Physical Stimulation

Share to Psychomotor Performance

Share to Sensation

Share to Temperature

Source

Open in PubMed Open full text

Identifiers

PMID: 33504822
DOI: 10.1038/s41598-021-81650-5
PMCID: PMC7840744

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comprehensive somatosensory and neurological phenotyping of NCS1 knockout mice.PMID 33504822Read ↗

Mouse behavioral genomics identifies Creld1 as a gatekeeper of somatosensationSemantic proximity Read ↗

Studies on CRMP2 SUMOylation-deficient transgenic mice identify sex-specific NaV1.7 regulation in the pathogenesis of chronic neuropathic painSemantic proximity Read ↗

Targeting Peripheral Somatosensory Neurons to Improve Tactile-Related Phenotypes in ASD Models.Semantic proximity Read ↗

Neuropsychological deficits in mice depleted of the schizophrenia susceptibility gene CSMD1.Semantic proximity Read ↗

Neuronal deletion of CaV1.2 is associated with sex-specific behavioral phenotypes in mice.Semantic proximity Read ↗

Global Nav1.7 knockout mice recapitulate the phenotype of human congenital indifference to pain.Semantic proximity Read ↗

Comprehensive phenotyping of sensory neurons using an ex vivo somatosensory system.Semantic proximity Read ↗

Alteration of inhibitory circuits in the somatosensory cortex of Ts65Dn mice, a model for Down’s syndromeSemantic proximity Read ↗

Gene expression profiling in trigeminal ganglia from Cntnap2 <sup>-/-</sup> and Shank3b <sup>-/-</sup> mouse models of autism spectrum disorderSemantic proximity Read ↗

Neurexophilin 3 is highly localized in cortical and cerebellar regions and is functionally important for sensorimotor gating and motor coordination.Semantic proximity Read ↗

Whisker stimulation alleviate ASD behavior of BTBR mice by regulating Piezo2 expression in DRG and neuron function in S1 and mPFCSemantic proximity Read ↗

Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.