Initial Whole-Genome Sequencing of Plasma Cell Neoplasms in First Responders and Recovery Workers Exposed to the World Trade Center Attack of September 11, 2001.

doi:10.1158/1078-0432.CCR-20-2245

Article

Initial Whole-Genome Sequencing of Plasma Cell Neoplasms in First Responders and Recovery Workers Exposed to the World Trade Center Attack of September 11, 2001.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Apr 2021

Maura Francesco, Diamond Benjamin, Maclachlan Kylee H, Derkach Andriy, Yellapantula Venkata D, Rustad Even H, Hultcrantz Malin, Shah Urvi A, Hong Jessica, Landau Heather J, Iacobuzio-Donahue Christine A, Papaemmanuil Elli, Irby Shani, Crowley Laura, Crane Michael, Webber Mayris P, Goldfarb David G, Zeig-Owens Rachel, Giricz Orsi, Verma Amit, Prezant David J, Dogan Ahmet, Shah Sohrab P, Zhang Yanming, Landgren Ola

Abstract excerpt

PURPOSE: The World Trade Center (WTC) attack of September 11, 2001 created an unprecedented environmental exposure to known and suspected carcinogens. High incidence of multiple myeloma and precursor conditions has been reported among first responders to the WTC disaster. To expand on our prior screening studies, and to characterize the genomic impact of the exposure to known and potential carcinogens in the WTC...

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