Article
Molecular determinants of agonist and antagonist signaling through the IL-36 receptor.
Journal of immunology (Baltimore, Md. : 1950) - 15 Jul 2014
Günther Sebastian, Sundberg Eric J
Abstract excerpt
The IL-1 family consists of 11 cytokines that control a complex network of proinflammatory signals critical for regulating immune responses to infections. They also play a central role in numerous chronic inflammatory disorders. Accordingly, inhibiting the activities of these cytokines is an impo...
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