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Article

Genetic variation in neuropeptide Y interacts with childhood trauma to influence anxiety sensitivity.

Anxiety, stress, and coping - 1 Jul 2021

Womersley Jacqueline Samantha, Martin Lindi, van der Merwe Lize, Seedat Soraya, Hemmings Sian Megan Joanna

Abstract excerpt

BACKGROUND AND OBJECTIVES: Anxiety sensitivity (AS) refers to a fear of the negative implications of anxiety, and arises due to gene-environment interactions. We investigated whether genetic variation in two neuropeptides implicated in the stress response, neuropeptide Y (NPY) and pituitary adenylate cyclase-activating polypeptide receptor 1, interacted with childhood trauma (CT) to influence AS. DESIGN AND...

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Source

Identifiers

PMID: 33491492
DOI: 10.1080/10615806.2021.1876225

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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