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Genetic Predisposition and Genetic Resilience Factors in Stress-Related Disorders During the Developmental Age: A Narrative Review.

Genes - 10 Nov 2025

Raffagnato Alessia, Raicich Arianna, Paiusco Lisa, Coser Giulia, Bonemazzi Ilaria, Gazzin Andrea, Pelizza Maria Federica, Ancora Caterina, Toldo Irene

Abstract excerpt

Background: Stress-related disorders, including PTSD, acute stress disorders, adjustment disorder, and attachment disorders, arise from complex interactions between genetic susceptibility and environmental stressors. While early environmental factors play a central role in the development of these disorders, there is growing evidence that genetic predisposition also contributes to individual differences in...

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Dopamine
Epigenesis, Genetic
Hypothalamo-Hypophyseal System
Norepinephrine
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Resilience, Psychological

Stress, Psychological

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Identifiers

PMID: 41300812
DOI: 10.3390/genes16111362
PMCID: PMC12652292

Genes

ACE
ADCYAP1R1
BDNF
COMT
FKBP5
HTR2A
MAOA
NR3C1
SLC6A4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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