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Article

Extending the vulnerability-stress model of mental disorders: three-dimensional NPSR1 × environment × coping interaction study in anxiety.

The British journal of psychiatry : the journal of mental science - 1 Nov 2020

Schiele Miriam A, Herzog Katharina, Kollert Leonie, Schartner Christoph, Leehr Elisabeth J, Böhnlein Joscha, Repple Jonathan, Rosenkranz Karoline, Lonsdorf Tina B, Dannlowski Udo, Zwanzger Peter, Reif Andreas, Pauli Paul, Deckert Jürgen, Domschke Katharina

Abstract excerpt

BACKGROUND: The general understanding of the 'vulnerability-stress model' of mental disorders neglects the modifying impact of resilience-increasing factors such as coping ability. AIMS: Probing a conceptual framework integrating both adverse events and coping factors in an extended 'vulnerability-stress-coping model' of mental disorders, the effects of functional neuropeptide S receptor gene (NPSR1) variation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32321595
DOI: 10.1192/bjp.2020.73
PMCID: PMC7589989

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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