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Article

An miRNA signature associated with tumor mutation burden in endometrial cancer.

Bioscience reports - 27 Nov 2020

Zhou Hongyu, Chen Lihua, Qin Mei, Lei Yajie, Li Tianjiao, Li Haoran, Cheng Xi

Abstract excerpt

Tumor mutation burden (TMB) is an essential biomarker to predict immunotherapy response. TMB measurement was mainly evaluated by whole-exome sequencing (WES), which was costly and difficult to be widely applied. In the present study, we aimed to establish and validate a miRNA signature to predict TMB level in endometrial cancer using The Cancer Genome Atlas (TCGA) database. MiRNA expression and somatic mutation...

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Identifiers

PMID: 33141168
DOI: 10.1042/BSR20203398
PMCID: PMC7670578

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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