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Article

Construction of a novel tumor mutation burden-related mRNA signature for prognosis prediction in laryngeal squamous cell carcinoma.

Medicine - 1 Nov 2024

Jiang Wen-Jing, Wang Chao, Hu Zhi-Hua, Jiang Xiao-Ze, Hu Wei-Ming

Abstract excerpt

Laryngeal squamous cell carcinoma (LSCC) is a common cancer with high mortality and tumor mutation burden (TMB), and high TMB is associated with favorable survival. The expression, mutation, and survival data were obtained from The Cancer Genome Atlas database. The mutation and differentially expressed genes were analyzed using limma R package. The function enrichment was analyzed by Gene Ontology and Kyoto...

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Identifiers

PMID: 39495979
DOI: 10.1097/MD.0000000000040431
PMCID: PMC11537643

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