Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Profiling of Orbital Fibroblasts from Patients with Graves’ Orbitopathy

23 Jan 2021

Abstract excerpt

CONTEXT: Graves' orbitopathy (GO) is an autoimmune disease that persists when immunosuppression is achieved. Orbital fibroblasts from GO patients display peculiar phenotypes even if not exposed to autoimmunity, possibly reflecting genetic or epigenetic mechanisms, which we investigated here. OBJECTIVE: We aimed to explore potential genetic or epigenetic differences using primary cultures of orbital fibroblasts...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Growth Hormone and Insulin-like Growth Factors
Share to Ophthalmology and Eye Disorders

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 33484567
DOI: 10.1210/clinem/dgab035

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Profiling of Orbital Fibroblasts from Patients with Graves’ OrbitopathyPMID 33484567Read ↗

Role of genetics and epigenetics in Graves' orbitopathy.Semantic proximity Read ↗

Emerging Insights Into the Role of Epigenetics and Gut Microbiome in the Pathogenesis of Graves’ OphthalmopathySemantic proximity Read ↗

Unravelling the pathogenic mechanisms in Graves’ orbitopathySemantic proximity Read ↗

Orbital Fibroblasts Exhibit a Novel Pattern of Responses to Proinflammatory Cytokines: Potential Basis for the Pathogenesis of Thyroid-Associated OphthalmopathySemantic proximity Read ↗

Pathogenic Phenotype of Adipogenesis and Hyaluronan in Orbital Fibroblasts From Female Graves' Orbitopathy Mouse Model.Semantic proximity Read ↗

Epigenetics effect on pathogenesis of thyroid-associated ophthalmopathySemantic proximity Read ↗

Current concepts in the molecular pathogenesis of thyroid-associated ophthalmopathy.Semantic proximity Read ↗

Dynamic transition of Tregs to cytotoxic phenotype amid systemic inflammation in Graves' ophthalmopathy.Semantic proximity Read ↗

Unique attributes of orbital fibroblasts and global alterations in IGF-1 receptor signaling could explain thyroid-associated ophthalmopathy.Semantic proximity Read ↗

Transcriptomic profiling of human orbital fat and differentiating orbital fibroblastsSemantic proximity Read ↗

Gene expression profiling of orbital muscles in treatment-resistant ophthalmoplegic myasthenia gravis.Semantic proximity Read ↗

Current perspectives on the role of orbital fibroblasts in the pathogenesis of Graves' ophthalmopathySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.