Article
One-Carbon Metabolism in Nepalese Infant-Mother Pairs and Child Cognition at 5 Years Old.
The Journal of nutrition - 8 Apr 2021
Kvestad Ingrid, McCann Adrian, Chandyo Ram K, Giil Lasse M, Shrestha Merina, Ulak Manjeswori, Hysing Mari, Ueland Per M, Strand Tor A
Abstract excerpt
BACKGROUND: One-carbon metabolism (OCM) refers to the transfer of methyl groups central to DNA methylation and histone modification. Insufficient access to methyl donors and B-vitamin cofactors affects epigenetic maintenance and stability, and when occurring in early life may impact future health and neurodevelopment. OBJECTIVE: The objective of this study was to examine the relative associations between...
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