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Methyl Donors, Epigenetic Alterations, and Brain Health: Understanding the Connection

25 Jan 2023

Abstract excerpt

Methyl donors such as choline, betaine, folic acid, methionine, and vitamins B6 and B12 are critical players in the one-carbon metabolism and have neuroprotective functions. The one-carbon metabolism comprises a series of interconnected chemical pathways that are important for normal cellular functions. Among these pathways are those of the methionine and folate cycles, which contribute to the formation of...

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PMID: 36768667
DOI: 10.3390/ijms24032346

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