Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

One-Carbon Metabolism: Linking Nutritional Biochemistry to Epigenetic Programming of Long-Term Development

9 Nov 2018

Abstract excerpt

One-carbon (1C) metabolism comprises a series of interlinking metabolic pathways that include the methionine and folate cycles that are central to cellular function, providing 1C units (methyl groups) for the synthesis of DNA, polyamines, amino acids, creatine, and phospholipids. S-adenosylmethionine is a potent aminopropyl and methyl donor within these cycles and serves as the principal substrate for methylation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Folate and B Vitamins Research
Share to Metabolism and Genetic Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30412672
DOI: 10.1146/annurev-animal-020518-115206

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

One-Carbon Metabolism: Linking Nutritional Biochemistry to Epigenetic Programming of Long-Term DevelopmentPMID 30412672Read ↗

One-carbon metabolism and epigenetic regulation of embryo developmentSemantic proximity Read ↗

The periconceptional period, reproduction and long-term health of offspring: the importance of one-carbon metabolismSemantic proximity Read ↗

Maternal nutritional status, C<sub>1</sub>metabolism and offspring DNA methylation: a review of current evidence in human subjectsSemantic proximity Read ↗

Epigenetics, Maternal Diet and Metabolic ProgrammingSemantic proximity Read ↗

Candidate genes linking maternal nutrient exposure to offspring health via DNA methylation: a review of existing evidence in humans with specific focus on one-carbon metabolismSemantic proximity Read ↗

One-Carbon Metabolism in Nepalese Infant-Mother Pairs and Child Cognition at 5 Years Old.Semantic proximity Read ↗

Polymorphisms in 1-carbon metabolism, epigenetics and folate-related pathologies.Semantic proximity Read ↗

Epigenetic Influences That Modulate Infant Growth, Development, and DiseaseSemantic proximity Read ↗

Methyl Donors, Epigenetic Alterations, and Brain Health: Understanding the ConnectionSemantic proximity Read ↗

Determinants of maternal pregnancy one-carbon metabolism and newborn human DNA methylation profiles.Semantic proximity Read ↗

Parental micronutrient deficiency distorts liver DNA methylation and expression of lipid genes associated with a fatty-liver-like phenotype in offspringSemantic proximity Read ↗

A crucial role for maternal dietary methyl donor intake in epigenetic programming and fetal growth outcomesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.