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Article

Role of ERCC5 polymorphisms in non‑small cell lung cancer risk and responsiveness/toxicity to cisplatin‑based chemotherapy in the Chinese population.

Oncology reports - 1 Mar 2021

Li Miao, Chen Rong, Ji Baoyan, Fan Chunmei, Wang Guanying, Yue Chenli, Jin Guoquan

Abstract excerpt

Non‑small cell lung cancer (NSCLC) is the leading cause of cancer‑related deaths worldwide. Cisplatin‑based chemotherapy currently represents the main treatment option for patients with NSCLC. The aim of the present study was to evaluate effect of single nucleotide polymorphisms (SNPs) within the excision repair cross‑complementing group 5 (ERCC5) gene on susceptibility to NSCLC, as well as the responsiveness to...

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Identifiers

PMID: 33469680
DOI: 10.3892/or.2021.7935

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