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Article

Role of ERCC1 variants in response to chemotherapy and clinical outcome of advanced non-small cell lung cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 May 2014

Huang Shao-jun, Wang Yu-fei, Jin Zhi-yong, Sun Jia-yang, Guo Zhan-lin

Abstract excerpt

Excision repair cross-complementation group 1 (ERCC1) and xeroderma pigmentosum-F (XPF) in the nucleotide excision repair pathway have been effectively repairing DNA damage induced by chemotherapeutic agents. We conducted a cohort study to assess the associations of ERCC1 and XPF polymorphisms with response to platinum-based chemotherapy and clinical outcome of non-small-cell lung cancer (NSCLC). One hundred...

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Aged
Carcinoma, Non-Small-Cell Lung
DNA-Binding Proteins
DNA Repair
Endonucleases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Treatment Outcome

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Identifiers

PMID: 24370899
DOI: 10.1007/s13277-013-1526-0

Genes

ERCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Role of ERCC1 variants in response to chemotherapy and clinical outcome of advanced non-small cell lung cancer.PMID 24370899Read ↗

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