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Article

Atypical phenotype and response of B cells in patients with seropositive rheumatoid arthritis.

Clinical and experimental immunology - 1 May 2021

Rincón-Arévalo H, Rojas M, Vanegas-García A, Muñoz-Vahos C, Orejuela-Erazo J, Vásquez G, Castaño D

Abstract excerpt

Patients with rheumatoid arthritis (RA) may be classified as seropositive or seronegative according to the presence of autoantibodies. An abnormal B cell phenotype and function could be one of the main components of the immunopathology of seropositive patients; however, there is little information regarding B cell defects in these patients. This study shows a broad characterization of the B cell phenotype and...

Topics

Adult
Aged
Arthritis, Rheumatoid
Autoantibodies
B-Lymphocytes
Cell Differentiation
Cytokines
Female
Humans
Immunoglobulin Isotypes
Immunologic Memory

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lymphocyte Activation

Male

Middle Aged

Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 33459349
DOI: 10.1111/cei.13576
PMCID: PMC8062998

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