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Rheumatoid Arthritis Related B‐Cell Changes Are Found Already in the Risk‐RA Phase

1 Feb 2025

Abstract excerpt

Anti-cyclic citrullinated peptide2 (CCP2) antibody positivity in rheumatoid arthritis (RA) and in the predisease phase, together with the success of B-cell depletion, support a crucial role for B cells in RA pathogenesis. Yet, knowledge of B cells in the transition from autoimmunity to RA is limited, and therefore we here investigated B-cell changes during the risk-RA phase. B-cell phenotypes in 18 CCP2-positive...

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Identifiers

PMID: 39931747
DOI: 10.1002/eji.202451391

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