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Article

Overcoming Obstacles to Targeting Muscarinic Receptor Signaling in Colorectal Cancer

13 Jan 2021

Abstract excerpt

Despite great advances in our understanding of the pathobiology of colorectal cancer and the genetic and environmental factors that mitigate its onset and progression, a paucity of effective treatments persists. The five-year survival for advanced, stage IV disease remains substantially less than 20%. This review examines a relatively untapped reservoir of potential therapies to target muscarinic receptor...

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PMID: 33450835
DOI: 10.3390/ijms22020716

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