Article
Recognize Yourself-Innate Sensing of Non-LTR Retrotransposons.
Viruses - 12 Jan 2021
Lagisquet Justine, Zuber Kilian, Gramberg Thomas
Abstract excerpt
Although mobile genetic elements, or transposons, have played an important role in genome evolution, excess activity of mobile elements can have detrimental consequences. Already, the enhanced expression of transposons-derived nucleic acids can trigger autoimmune reactions that may result in severe autoinflammatory disorders. Thus, cells contain several layers of protective measures to restrict transposons and to...
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