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Article

Combining Structural-Equation Modeling with Genomic-Relatedness-Matrix Restricted Maximum Likelihood in OpenMx.

Behavior genetics - 1 May 2021

Kirkpatrick Robert M, Pritikin Joshua N, Hunter Michael D, Neale Michael C

Abstract excerpt

There is a long history of fitting biometrical structural-equation models (SEMs) in the pregenomic behavioral-genetics literature of twin, family, and adoption studies. Recently, a method has emerged for estimating biometrical variance-covariance components based not upon the expected degree of genetic resemblance among relatives, but upon the observed degree of genetic resemblance among unrelated individuals for...

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Identifiers

PMID: 33439421
DOI: 10.1007/s10519-020-10037-5
PMCID: PMC8096671

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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