Article
Revisiting the Children-of-Twins Design: Improving Existing Models for the Exploration of Intergenerational Associations.
Behavior genetics - 1 Sept 2018
McAdams Tom A, Hannigan Laurie J, Eilertsen Espen Moen, Gjerde Line C, Ystrom Eivind, Rijsdijk Fruhling V
Abstract excerpt
Datasets comprising twins and their children can be a useful tool for understanding the nature of intergenerational associations between parent and offspring phenotypes. In the present article we explore structural equation models previously used to analyse Children-of-Twins data, highlighting some limitations and considerations. We then present new variants of these models, showing that extending the models to...
Topics
- Child
- Computer Simulation
- Family Characteristics
- Humans
- Models, Biological
- Parents
- Phenotype
- Twins