Article
Genetic and environmental determinants of variation in the plasma lipidome of older Australian twins.
eLife - 22 Jul 2020
Wong Matthew Wk, Thalamuthu Anbupalam, Braidy Nady, Mather Karen A, Liu Yue, Ciobanu Liliana, Baune Bernhardt T, Armstrong Nicola J, Kwok John, Schofield Peter, Wright Margaret J, Ames David, Pickford Russell, Lee Teresa, Poljak Anne, Sachdev Perminder S
Abstract excerpt
The critical role of blood lipids in a broad range of health and disease states is well recognised but less explored is the interplay of genetics and environment within the broader blood lipidome. We examined heritability of the plasma lipidome among healthy older-aged twins (75 monozygotic/55 dizygotic pairs) enrolled in the Older Australian Twins Study (OATS) and explored corresponding gene expression and DNA...
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