Article
Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.
PLoS genetics - 1 Jan 2012
Demirkan Ayşe, van Duijn Cornelia M, Ugocsai Peter, Isaacs Aaron, Pramstaller Peter P, Liebisch Gerhard, Wilson James F, Johansson Åsa, Rudan Igor, Aulchenko Yurii S, Kirichenko Anatoly V, Janssens A Cecile J W, Jansen Ritsert C, Gnewuch Carsten, Domingues Francisco S, Pattaro Cristian, Wild Sarah H, Jonasson Inger, Polasek Ozren, Zorkoltseva Irina V, Hofman Albert, Karssen Lennart C, Struchalin Maksim, Floyd James, Igl Wilmar, Biloglav Zrinka, Broer Linda, Pfeufer Arne, Pichler Irene, Campbell Susan, Zaboli Ghazal, Kolcic Ivana, Rivadeneira Fernando, Huffman Jennifer, Hastie Nicholas D, Uitterlinden Andre, Franke Lude, Franklin Christopher S, Vitart Veronique, Nelson Christopher P, Preuss Michael, Bis Joshua C, O'Donnell Christopher J, Franceschini Nora, Witteman Jacqueline C M, Axenovich Tatiana, Oostra Ben A, Meitinger Thomas, Hicks Andrew A, Hayward Caroline, Wright Alan F, Gyllensten Ulf, Campbell Harry, Schmitz Gerd
Abstract excerpt
Phospho- and sphingolipids are crucial cellular and intracellular compounds. These lipids are required for active transport, a number of enzymatic processes, membrane formation, and cell signalling. Disruption of their metabolism leads to several diseases, with diverse neurological, psychiatric,...
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