Article
Major Histocompatibility Complex Class I-Related Chain A Alleles and Histology of Nonalcoholic Fatty Liver Disease.
Hepatology communications - 1 Jan 2021
Karrar Azza, Rajput Bijal, Hariharan Siddharth, Abdelatif Dinan, Houry Mohamad, Moosvi Ali, Ali Irfan, Tan Daisong, Noor Sohailla, Esmaeili Donna, Felix Sean, Alaparthi Lakshmi, Otgonsuren Munkhzul, Lam Brian, Goodman Zachary D, Younossi Zobair M
Abstract excerpt
Major histocompatibility complex class I-related chain A (MICA) is a highly polymorphic gene that modulates immune surveillance by binding to its receptor on natural killer cells, and its genetic polymorphisms have been associated with chronic immune-mediated diseases. The progressive form of nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), is characterized by accumulation of fat and...
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