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Analysis of human leukocyte antigen allele polymorphism in patients with non alcoholic fatty liver disease

1 Aug 2019

Abstract excerpt

The human leukocyte antigen (HLA) genes may play a role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD) and its progressive form, non-alcoholic steatohepatitis (NASH). The aim of this study was to assess the association of HLA class I and II alleles with NASH and its histological features.Deoxyribonucleic acid (DNA) was extracted from 140 subjects (85 biopsy-proven NAFLD and 55 controls) and...

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PMID: 31393374
DOI: 10.1097/md.0000000000016704

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