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Article

Regulation of the expression of the liver cancer susceptibility gene MICA by microRNAs.

Scientific reports - 1 Jan 2013

Kishikawa Takahiro, Otsuka Motoyuki, Yoshikawa Takeshi, Ohno Motoko, Takata Akemi, Shibata Chikako, Kondo Yuji, Akanuma Masao, Yoshida Haruhiko, Koike Kazuhiko

Abstract excerpt

Hepatocellular carcinoma (HCC) is a threat to public health worldwide. We previously identified the association of a single nucleotide polymorphism (SNP) at the promoter region of the MHC class I polypeptide-related sequence A (MICA) gene with the risk of hepatitis-virus-related HCC. Because this SNP affects MICA expression levels, regulating MICA expression levels may be important in the prevention of HCC. We...

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Identifiers

PMID: 24061441
DOI: 10.1038/srep02739
PMCID: PMC3781398

Genes

MICA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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