Article
HLA DQB1 alleles are related with nonalcoholic fatty liver disease.
Molecular biology reports - 1 Dec 2014
Doganay Levent, Katrinli Seyma, Colak Yasar, Senates Ebubekir, Zemheri Ebru, Ozturk Oguzhan, Enc Feruze Yilmaz, Tuncer Ilyas, Doganay Gizem Dinler
Abstract excerpt
Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease. NAFLD is a complex disease and inflammation is a crucial component in the disease pathogenesis. Recent genome wide association studies in hepatology area highlighted significant relations with human leukocyte antigen (HLA) DQ region and certain liver diseases. The previous animal models also emphasized the involvement of...
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