Article
Analysis of Interleukin-1 Signaling Alterations of Colon Adenocarcinoma Identified Implications for Immunotherapy.
Frontiers in immunology - 1 Jan 2021
Zhou Xiaogang, Liu Yu, Xiang Jing, Wang Yuntao, Wang Qiqian, Xia Jianling, Chen Yunfei, Bai Yifeng
Abstract excerpt
Immune checkpoint inhibitors (ICIs) have made breakthrough progress in the treatment of various malignant tumors. However, only some patients receiving ICIs obtain long-lasting clinical effects, and some patients still do not achieve remission. Improving the treatment benefits of this part of the population has become a concern of clinicians. IL-1 signaling plays an important role in the tumor microenvironment...
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