Article
The Role of Mannose-binding Lectin in Infectious Complications of Pediatric Hemato-Oncologic Diseases.
The Pediatric infectious disease journal - 1 Feb 2021
Dobi Marianna, Szilágyi Ágnes, Csuka Dorottya, Varga Lilian, Prohászka Zoltán, Bereczki Csaba, Kovács Gábor, Fekete Ferenc
Abstract excerpt
The complement system is essential for protection against infections in oncologic patients because of the chemotherapy-induced immunosuppression. One of the key elements in the activation of the complement system via the lectin pathway is the appropriate functioning of mannose-binding lectin (MBL) and mannose-binding lectin-associated serine protease 2 (MASP2) complex. The objective of our study was to find an...
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