Article
The role of mannose-binding lectin (MBL) in paediatric oncology patients with febrile neutropenia.
European journal of cancer (Oxford, England : 1990) - 1 May 2006
Frakking F N J, van de Wetering M D, Brouwer N, Dolman K M, Geissler J, Lemkes B, Caron H N, Kuijpers T W
Abstract excerpt
Children with cancer often have fever during chemotherapy-induced neutropenia, but only some develop serious infectious complications. Mannose-binding lectin (MBL) deficiency might increase infection susceptibility in these children. MBL genotype and phenotype were prospectively determined in 110 paediatric oncology patients. During febrile neutropenia, MBL concentrations were measured longitudinally in time. MBL...
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