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Article

Effect of TRAF1 on Phenotypic Changes Of Kupffer Cells In Liver Transplantation Ischemic-Reperfusion.

Current pharmaceutical biotechnology - 1 Jan 2021

Zhang Zhen, Que KeTing, You Yu, Zhao XiaoPing, Wen DiGuang, Feng ZhiHao, Liu ZuoJin

Abstract excerpt

OBJECTIVE: The purpose of this study was to explore the effect of TRAF1 on phenotypic changes of KCs in I/R in liver transplantation. METHODS: SD rats were randomly divided into sham group and liver transplantation I/R group. KCs were extracted from rat livers in each group. KCs were transfected by lentivirus of si-TRAF1 or si-HOIP, and induced by Lipopolysaccharide (LPS). Flow cytometry was used to detect cell...

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PMID: 33430723
DOI: 10.2174/1389201022666210111113900

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