Article
Cell competition: winning out by losing notch.
Cell cycle (Georgetown, Tex.) - 1 Jan 2015
Alcolea Maria P, Jones Philip H
Abstract excerpt
Cell competition where 'loser' cells are eliminated by neighbors with higher fitness is a widespread phenomenon in development. However, a growing body of evidence argues cells with somatic mutations compete with their wild type counterparts in the earliest stages of cancer development. Recent studies have begun to shed light on the molecular and cellular mechanisms that alter the competitiveness of cells...
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