Article
Novel Recurrent Altered Genes in Chinese Patients With Anaplastic Thyroid Cancer.
The Journal of clinical endocrinology and metabolism - 25 Mar 2021
Zhang Lingyun, Ren Zhixiang, Su Zhengzheng, Liu Yang, Yang Tian, Cao Minyuan, Jiang Yong, Tang Ying, Chen Haining, Zhang Weihan, Gong Rixiang, Wei Tao, Peng Yong, Liu Bo, Zhang Wei, Yang Li, Hu Yiguo, Li Zhihui, Zhu Jingqiang, Xu Heng, Shu Yang, Luo Han
Abstract excerpt
BACKGROUND: Anaplastic thyroid cancer (ATC) is a rare but lethal malignancy, and few systematic investigations on genomic profiles of ATC have been performed in Chinese patients. METHODS: Fifty-four ATC patients in West China Hospital between 2010 to 2020 were retrospectively analyzed, while 29 patients with available samples were sequenced by whole-exome sequencing (WES). The associations between genomic...
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