Article

The long non-coding RNA NEAT1 regulates the transcriptional landscape of cardiomyocytes

2024-06-27

Abstract excerpt

Long non-coding RNAs (lncRNAs) play a crucial role in fine-tuning the gene expression. In the present study, we identified that the lncRNA NEAT1 is upregulated in failing murine hearts and in human hypertrophic cardiomyopathies. Further investigations demonstrated that NEAT1 expression is regulated by calcium dependent NFAT (nuclear factor of activated T cells). Overexpression of NEAT1 led to increased cardiomyocy...

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Literature Corpus work: 57b7ddf4-d6eb-5af1-bd51-26d71d8a33ad
DOI: 10.1101/2024.06.27.600932

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