Article
Benchmarking HLA genotyping and clarifying HLA impact on survival in tumor immunotherapy.
Molecular oncology - 1 Jul 2021
Li Xiangyong, Zhou Chi, Chen Ke, Huang Bingding, Liu Qi, Ye Hao
Abstract excerpt
Human leukocyte antigen (HLA) genotyping gains intensive attention due to its critical role in cancer immunotherapy. It is still a challenging issue to generate reliable HLA genotyping results through in silico tools. In addition, the survival impact of HLA alleles in tumor prognosis and immunotherapy remains controversial. In this study, the benchmarking of HLA genotyping on TCGA is performed and a 'Gun-Bullet'...
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