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Article

The N-terminus of varicella-zoster virus glycoprotein B has a functional role in fusion.

PLoS pathogens - 1 Jan 2021

Oliver Stefan L, Xing Yi, Chen Dong-Hua, Roh Soung Hun, Pintilie Grigore D, Bushnell David A, Sommer Marvin H, Yang Edward, Carfi Andrea, Chiu Wah, Arvin Ann M

Abstract excerpt

Varicella-zoster virus (VZV) is a medically important alphaherpesvirus that induces fusion of the virion envelope and the cell membrane during entry, and between cells to form polykaryocytes within infected tissues during pathogenesis. All members of the Herpesviridae, including VZV, have a conserved core fusion complex composed of glycoproteins, gB, gH and gL. The ectodomain of the primary fusogen, gB, has five...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33411789
DOI: 10.1371/journal.ppat.1008961
PMCID: PMC7817050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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