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Article

An immunoreceptor tyrosine-based inhibition motif in varicella-zoster virus glycoprotein B regulates cell fusion and skin pathogenesis.

Proceedings of the National Academy of Sciences of the United States of America - 29 Jan 2013

Oliver Stefan L, Brady Jennifer J, Sommer Marvin H, Reichelt Mike, Sung Phillip, Blau Helen M, Arvin Ann M

Abstract excerpt

Herpesvirus entry functions of the conserved glycoproteins gB and gH-gL have been delineated, but their role in regulating cell-cell fusion is poorly understood. Varicella-zoster virus (VZV) infection provides a valuable model for investigating cell-cell fusion because of the importance of this process for pathogenesis in human skin and sensory ganglia. The present study identifies a canonical immunoreceptor...

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Identifiers

PMID: 23322733
DOI: 10.1073/pnas.1216985110
PMCID: PMC3562845

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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